Insulin-like Growth Factor-1 Receptor Inhibitors

Abhijit Roychowdhury, Rajiv Sharma, Malcolm Mascarenhas, Chandrika B-Rao, Shashikant M Patil, Sambhaji Chavan, Nitin Lad, Smriti Khanna, Christopher J Dinsmore

October 2013

Abstract

The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating Insulin-Like Growth Factor I Receptor and Insulin Receptor. The compounds of the instant invention possess a core structure that comprises a sulfonyl indole moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.

Type

Patent

Publication

Patent: WO 2013/148227

IGF-1R inhibitors

Chandrika B-Rao

Independent Consultant

Drug Discovery, Bioinformatics and Statistics