Publications and Patents

Smriti Khanna, Chandrika B-Rao, Usha Ghosh, Zejah Rizvi, Komal Bajaj, Asha Kulkarni-Almeida, Rajiv Sharma (2016). Discriminating between active and inactive compounds using binding energy calculations – a case study. Biointerface Research in Applied Chemistry 6(4):1422-1427.

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Valmik Sopan Aware, Nitin Gaikwad, Sambhaji Chavan, Sonal Manohar, Julie Bose, Smriti Khanna, Chandrika B-Rao, Neeta Dixit, Kishori Sharan Singh, Anagha Damre, Rajiv Sharma, Sambhaji Patil, Abhijit Roychowdhury (2015). Cyclopentyl-pyrimidine based analogues as novel and potent IGF-1R inhibitor. European Journal of Medicinal Chemistry 92:246-256.

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Nabajyoti Deka, Swapnil Bajare, Jessy Anthony, Amrutha Nair, Anagha Damre, Dharmeshkumar Patel, Chandrika B-Rao, H. Sivaramakrishnan, Shivaprakash Jagalur Mutt, Chandan Wilankar, Rosalind Marita (2013). Synthesis of N-(6-(4-(Piperazin-1-yl)phenoxy)pyridin-3-yl)benzenesulfonamide Derivatives for the Treatment of Metabolic Syndrome. International Journal of Medicinal Chemistry.

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Nabajyoti Deka, Mahesh Uravane, Jessy Anthony, Sujit Bhumra, Amrutha Nair, Chandrika B-Rao, Dharmeshkumar Patel, H. Sivaramakrishnan (2013). Design and synthesis of non-TZD peroxisome proliferator-activated receptor γ (PPARγ) modulator. Medicinal Chemistry Research 23(4).

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Abhijit Roychowdhury, Rajiv Sharma, Malcolm Mascarenhas, Chandrika B-Rao, Shashikant M Patil, Sambhaji Chavan, Nitin Lad, Smriti Khanna, Christopher J Dinsmore (2013). Insulin-like Growth Factor-1 Receptor Inhibitors. Patent: WO 2013/148227.

Komal Bajaj, Sandeep Burudkar, Pranay Shah, Ashish Keche, Usha Ghosh, Prashant Tannu, Smriti Khanna, Ankita Srivastava, Nitin J. Deshmukh, Amol Dixit, Yogesh Ahire, Anagha Damre, Kumar V.S. Nemmani, Asha Kulkarni-Almeida, Chandrika B-Rao, Rajiv Sharma, H. Sivaramakrishnan (2013). Lead optimization of isocytosine-derived xanthine oxidase inhibitors. Bioorganic & Medicinal Chemistry Letters 23(3).

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Swapnil Bajare, Jessy Anthony, Amrutha Nair, Rosalind Marita, Anagha Damre, Dharmeshkumar Patel, Chandrika B-Rao, H Sivaramakrishnan, Nabajyoti Deka (2012). Synthesis of N-(5-chloro-6-(quinolin-3-yloxy)pyridin-3-yl)benzenesulfonamide derivatives as non-TZD peroxisome proliferator-activated receptor γ (PPARγ) agonist. European Journal of Medicinal Chemistry 58C:355-360.

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Smriti Khanna, Sandeep Burudkar, Komal Bajaj, Pranay Shah, Ashish Keche, Usha Ghosh, Avani Desai, Ankita Srivastava, Asha Kulkarni-Almeida, Nitin J Deshmukh, Amol Dixit, Manoja K Brahma, Umakant Bahirat, Lalit Doshi, Kumar V S Nemmani, Prashant Tannu, Anagha Damre, Chandrika B-Rao, Rajiv Sharma, H Sivaramakrishnan (2012). Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia. Bioorganic & Medicinal Chemistry Letters 22(24).

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Chandrika B-Rao, Asha Kulkarni-Almeida, Kamlesh V Katkar, Smriti Khanna, Usha Ghosh, Ashish Keche, Pranay Shah, Ankita Srivastava, Vaidehi Korde, Kumar V S Nemmani, Nitin J Deshmukh, Amol Dixit, Manoja K Brahma, Umakant Bahirat, Lalit Doshi, Rajiv Sharma, H Sivaramakrishnan (2012). Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits. Bioorganic & Medicinal Chemistry 20(9):2930-9.

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B Ghosh, R Nagarkatti, Chandrika B-Rao (2010). A method for detecting predisposition to atopic disorders by screening for human signal transducer and Activator of Transcription-6 (STAT-6) gene variants. United States Patent (No. 7671182).

Ritushree Kukreti, Pallav Bhatnagar, Chandrika B-Rao, B Ghosh, Samir K Brahmachari, Randeep Guleria, Chiranjit Das (2009). A method for predicting an individual’s bronchodilatory response to a beta agonist. Patent: Korea (No. 10-0924371).

Chandrika B-Rao, Jyothi Subramanian, Somesh D Sharma (2009). Managing protein flexibility in docking and its applications. Drug Discovery Today 14(7-8):394-400.

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Nilesh M Dagia, Divya V Kamath, Pooja Bhatt, Ravindra D Gupte, Shruta S Dadarkar, Lyle Fonseca, Gautam Agarwal, Anshu Chetrapal-Kunwar, Sarala Balachandran, Shaila Srinivasan, Julie Bose, Koteppa Pari, Chandrika B-Rao, Santosh S Parkale, Pradip K Gadekar, Atish H Rodge, Noopur Mandrekar, Ram A Vishwakarma, Somesh Sharma (2009). A fluorinated analog of ISO-1 blocks the recognition and biological function of MIF and is orally efficacious in a murine model of colitis. European Journal of Pharmacology 607(1-3):201-12.

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S K Brahmachari, Srinivasan Ramachandran, Tannistha Nandi, Chandrika B-Rao (2008). A novel computational method for the identification of candidate proteins useful as anti-infectives. United States Patent No. 7363166.

Jyothi Subramanian, Somesh Sharma, Chandrika B-Rao (2008). Modeling and Selection of Flexible Proteins for Structure‐Based Drug Design: Backbone and Side Chain Movements in p38 MAPK. ChemMedChem 3(2):336-44.

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Jyothi Subramanian, Somesh Sharma, Chandrika B-Rao (2006). A Novel Computational Analysis of Ligand-Induced Conformational Changes in the ATP Binding Sites of Cyclin Dependent Kinases. Journal of Medicinal Chemistry 49(18):5434-41.

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Ranjana Verma, Mitali Mukerji, Deepak Grover, Chandrika B-Rao, Swapan Kumar Das, Shobana Kubendran, Sanjeev Jain, Samir K Brahmachari (2005). MLC1 Gene Is Associated with Schizophrenia and Bipolar Disorder in Southern India. Biological Psychiatry 58(1):16-22.

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Ritushree Kukreti, Pallav Bhatnagar, Chandrika B-Rao, Simone Gupta, Babita Madan, Chinmoyee Das, Randeep Guleria, Amita Umesh Athavale, Samir Kumar Brahmachari, Balaram Ghosh (2005). β2-adrenergic receptor polymorphisms and response to salbutamol among Indian asthmatics. Pharmacogenomics 6(4):399-410.

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Kamalpreet Nagpal, Shilpy Sharma, Chandrika B-Rao, Sanober Nahid, Pramod V Niphadkar, Surendra K Sharma, Balaram Ghosh (2005). TGFβ1 haplotypes and asthma in Indian populations. Journal of Allergy and Clinical Immunology 115(3):527-33.

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S Sharma, R Nagarkatti, Chandrika B-Rao, P V Niphadkar, V Vijayan, S K Sharma, B Ghosh (2004). A_16_C haplotype in the FcεRIβ gene confers a higher risk for atopic asthma in the Indian population. Clinical Genetics 66(5):417-25.

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Rana Nagarkatti, Chandrika B-Rao, Vannankandi Vijayan, Surendra K. Sharma, Balaram Ghosh (2004). Signal Transducer and Activator of Transcription 6 Haplotypes and Asthma in the Indian Population. American Journal of Respiratory Cell and Molecular Biology 31(3):317-21.

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Aparna Chattopadhyay, Asis Kumar Chattopadhyay, Chandrika B-Rao (2004). Bhattacharyya's distance measure as a precursor of genetic distance measures. Journal of Biosciences 29(2):135-8.

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Vineet K Sharma, Chandrika B-Rao, Anu Sharma, Samir K Brahmachari, Srinivasan Ramachandran (2003). (TG/CA)n Repeats in Human Housekeeping Genes. Journal of biomolecular Structure & Dynamics 21(2):303-10.

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Deepak Grover, Partha P Majumder, Chandrika B-Rao, Samir K Brahmachari, Mitali Mukerji (2003). Nonrandom Distribution of Alu Elements in Genes of Various Functional Categories: Insight from Analysis of Human Chromosomes 21 and 22. Molecular Biology and Evolution 20(9):1420-4.

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Tannistha Nandi, Debasis Dash, Rohit Ghai, Chandrika B-Rao, K Kannan, Samir K Brahmachari, C Ramakrishnan, Srinivasan Ramachandran (2003). A Novel Complexity Measure for Comparative Analysis of Protein Sequences from Complete Genomes. Journal of biomolecular Structure & Dynamics 20(5):657-68.

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Rana Nagarkatti, Chandrika B-Rao, Jai Prakash Rishi, Rajesh Chetiwal, Vipul Shandilya, Vannankandi Vijayan, Raj Kumar, Harish K Pemde, Surendra K Sharma, Sweety Sharma, Anand B Singh, Sharad V Gangal, Balaram Ghosh (2002). Association of IFNG gene polymorphism with asthma in the Indian population. The Journal of allergy and clinical immunology 110(3).

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Tannistha Nandi, Chandrika B-Rao, Srinivasan Ramachandran (2002). Comparative genomics using data mining tools. Journal of Biosciences 27(1 Suppl 1):15-2.

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Ritushree Kukreti, Chandrika B-Rao, Swapan Kr Das, Madhusnata De, Geeta Talukder, Flavian Vaz, I C Verma, Samir K Brahmachari (2002). Study of the single nucleotide polymorphism (SNP) at the palindromic sequence of hypersensitive site (HS)4 of the human beta-globin locus control region (LCR) in Indian population. American Journal of Hematology 69(1):77-9.

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Chandrika B-Rao (2001). Sample Size Considerations in Genetic Polymorphism Studies. Human Heredity 52(4):191-200.

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Quasar Saleem, V.S. Sreevidya, J. Sudhir, J. Vijaya Savithri, Y. Gowda, Chandrika B-Rao, V. Benegal, Partha P. Majumder, Anuranjan Anand, Samir K. Brahmachari, Sanjeev Jain (2000). Association analysis of CAG repeats at the KCNN3 locus in Indian patients with bipolar disorder and schizophrenia. American Journal of Medical Genetics 96(6):744-8.

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Chandrika B-Rao, Kshitish C. Majumdar (1999). Reconstruction of phylogenetic relationships. Journal of Biosciences 24(1):121-137.

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Chandrika B-Rao, K. C. Majumdar (1998). Multivariate map representation of phylogenetic relationships: application to tilapiine fish. Journal of Fish Biology 52(6):1199 - 1217.

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Chandrika B-Rao, John Stewart (1996). Inverse analysis of empirical matrices of idiotypic network interactions. Bulletin of Mathematical Biology 58(6):1123-1153.

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Chandrika B-Rao, R R Joshi (1990). Stochastic inventory analysis of antibody production. Computers & Mathematics with Applications 20(8):37-49.

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Chandrika B-Rao, R R Joshi (1989). On antigen-antibody binding distributions. Journal of Theoretical Biology 141(3):285-302.

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