Genetics of Neuropsychiatric disorders

MLC1 Gene Is Associated with Schizophrenia and Bipolar Disorder in Southern India

Background Chromosome 22q13 has shown linkage with schizophrenia (SCZ) and bipolar affective disorder (BPAD). A missense mutation in MLC1 (putative cation-channel gene on 22q13) co-segregating with periodic catatonic schizophrenia has been reported. …

Association analysis of CAG repeats at the KCNN3 locus in Indian patients with bipolar disorder and schizophrenia

Bipolar affective disorder and schizophrenia are severe behavioral disorders with a lifetime risk of approximately 1% in the population worldwide. There is evidence that these diseases may manifest the phenomenon of anticipation similar to that seen …